​第11回

堀木 充 先生

論文名

Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia

坂本 昭夫 先生

論文名

Chondrocyte-specific knockout of the G Protein Gs  leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation.

筑田 博隆 先生

論文名

Cyclic GMP-dependent protein kinase Ⅱ  is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes

雑誌名

The Journal of Cell Biology

​巻号ページ

165(3):433-445,2004

雑誌名

The Journal of Bone and Mineral

​巻号ページ

20(4):663-671 (2005)

雑誌名

GENES & DEVELOPMENT

​巻号ページ

18:2418-2429,2004

山本 浩司 先生

論文名

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

第12回

坂口 祐輔 先生

論文名

Superiority of synovium as cell source: Comparison of human stem cells derived from various mesenchymal tissues

神谷 宣広 先生

論文名

Versican/PG-M Regulates Chondrogenesis as an Extracellular Matrix Molecule Crucial for Mesenchymal Condensation

吉富 啓之 先生

論文名

A role for fungal  β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

今村 寿宏 先生

論文名

Transcriptional Co-activators CREB-binding Protein/p300 Increase Chondrocyte Cd-rap Gene Expression by Multiple Mechanisms CCAAT/Enhancer-binding Protein

井上 敦夫 先生

論文名

The Therapeutic Effects of Basic Fibroblast Growth Factor Contained in Gelatin Hydrogel Microspheres on Experimental Osteoarthritis in the Rabbit Knee

雑誌名

Arthritis and Rheumatism

​巻号ページ

52(8):2521-2529,2005

雑誌名

The Journal of Biological Chemistry

​巻号ページ

281(4):2390-2400,2006

雑誌名

Journal of Experimental Medicine

​巻号ページ

201(6):949-960,2005

雑誌名

The Journal of Biological Chemistry

​巻号ページ

280(17):16625-16634,2005

雑誌名

Arthritis and Rheumatism

​巻号ページ

54(1):264-270,2006

​第13回

坂井 顕一郎 先生

論文名

Chondroitin Sulfate N-Acetylgalactosaminyltransferase-1 Plays a Critical Role in Chondroitin Sulfate Synthesis in Cartilage

秋山 治彦 先生

論文名

Osteo-chondroprogenitor cells are derived from SOX9 expressing precursors

古松 毅之 先生

論文名

SOX9 and p300 cooperatively regulate chromatin-mediated transcription

斎藤 琢 先生

論文名

S100A1 and S100B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes

平尾 眞 先生

論文名

Oxygen Tension Regulates Chondrocyte Differentiation and Function during Endochondral Ossification

雑誌名

The Journal of Biological Chemistry

​巻号ページ

282(6):4152-4161,2007

雑誌名

PNAS

​巻号ページ

102(41):14665-146710,2005

雑誌名

The Journal of Biological Chemistry

​巻号ページ

280(42):35203-35208,2005

雑誌名

EMBO Reports

​巻号ページ

8(5):504-509,2007

雑誌名

The Journal of Biological Chemistry

​巻号ページ

281(41):31079-31092,2006

第14回

中村 幸男 先生

論文名

The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signaling

山田 高嗣 先生

論文名

Carminerin contributes to chondrocyte calcification during endochondral ossification

 森田 晃造,  宮本 健史 先生

論文名

Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification

江口 傑徳 先生

論文名

Novel Transcription Factor-Like Function of Human Matrix Metalloproteinase 3 Regulating the CTGF/CCN2 Gene

雑誌名

The Journal of Clinical Investigation

​巻号ページ

117(10):3075-3086,2007

雑誌名

Nature Medicine

​巻号ページ

12(6):665-670,2006

雑誌名

The Journal of Experimental Medicine

​巻号ページ

204:1613-1623,2007

雑誌名

Molecular & Cellular Biology

​巻号ページ

28(7):2391-2413,2008

雑誌名

The American Journal of Human Genetics

​巻号ページ

81:1271-1277,2007

三尾 太 先生

論文名

A Functional Polymorphism in COL11A1, Which Encodes the α1 Chain of Type X1 Collagen, Is Associated with Susceptibility to Lumbar Disc Herniation

​第15回

川崎 洋介 先生

論文名

Phosphorylation of GSK-3β by cGMP-dependent protein kinase ? promotes hypertrophic differentiation of murine chondrocytes

岡田 愛子 先生

論文名

ADAM-12(Meltrin α) Is Involved in Chondrocyte Proliferation via Clearvage of Insulin-like Growth Factor Binding Protein 5 in Osteoarthritic Cartilage

廣瀬 裕一郎 先生

論文名

A Functional Polymorphism in THBS2 that Affects Alternative Splicing and MMP Binding Is Associated with Lumbar-Disc Herniation

岩井 貴男 先生

論文名

Smad7 Inhibits Chondrocyte Differentiation at Multiple Steps during Endochondral Bone Formation and Down-regulates p38 MAPK Pathways

雑誌名

The Journal of Clinical Investigation

​巻号ページ

118:2506-2515,2008

雑誌名

ARTHRITIS & RHEUMATISM

​巻号ページ

58(3):778-789,March 2008

雑誌名

The American Journal of Human Genetics

​巻号ページ

82:1122-1129,May 2008

雑誌名

The Journal of Biological Chemistry

​巻号ページ

283(40):27154-27164,Oct. 2008

雑誌名

PLoS ONE

​巻号ページ

4(2):e4543,February 2009

谷口 昇 先生

論文名

Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis

平田 真 先生

論文名

C/EBPβ Promotes Transition from Proliferation to Hypertrophic Differentiation of Chondrocytes through Transactivation of p57Kip2

雑誌名

The National Academy of Sciences of the USA

​巻号ページ

106(4):1181-1186,January 2009

​第16回

菅 哲徳 先生

論文名

Screening of Chondrogenic Factors With a Real-time Fluorescence-Monitoring Cell Line ATDC5-C2ER Identification of Sorting Nexin 19 as a Novel Factor

北折 俊之 先生

論文名

Stromal Cell-Derived Factor 1/CXCR4 Signaling Is Critical for the Recruitment of Mesenchymal Stem Cells to the Fracture Site During Skeletal Repair in a Mouse Model

林田 光正 先生

論文名

CCAAT/Enhancer Binding Protein βMediates Expression of Matrix Metalloproteinase 13 in Human Articular Chondrocytes in Inflammatory Arthritis

深井 厚 先生

論文名

Akt1 in Murine Chondrocytes Controls Cartilage Calcification Durting Endochondral Ossification Under Physiologic and Pathologic Conditions

雑誌名

ARTHRITIS & RHEUMATISM

​巻号ページ

60(11): 3314-3323,November 2009

雑誌名

ARTHRITIS & RHEUMATISM

​巻号ページ

60(3): 813-823,March 2009

雑誌名

ARTHRITIS & RHEUMATISM

​巻号ページ

60(3): 708-716,March 2009

雑誌名

ARTHRITIS & RHEUMATISM

​巻号ページ

62(3): 826-836,March 2010

松井 雄一郎 先生

論文名

Accelerated Development of Aging-Associated and Instability-Induced Osteoarthritis in Osteopontin-Deficient Mice

雑誌名

ARTHRITIS & RHEUMATISM

​巻号ページ

60(8): 2362-2371,August 2009

​第17回

伊藤 義晃 先生

論文名

The Mohawk homeobox gene is a critical regulator of tendon differentiation

雑誌名

Proc Natl Acad Sci U S A.

​巻号ページ

107(23):10538-42,June 2010

雑誌名

Proc Natl Acad Sci U S A.

​巻号ページ

107(22):10202-7,June 2010

雑誌名

American Journal of Pathology

​巻号ページ

176(6):2858-67,June 2010

檜山 明彦 先生

論文名

Enhancement of Intervertebral Disc Cell Senescence by WNT/β-Catenin Signaling -Induced Matrix Metalloproteinase Expression

雑誌名

Arthritis & Rheumatism

​巻号ページ

62(10):3036-47,October 2010

山本 浩司 先生

論文名

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

大槻 周平先生

論文名

Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways

木村 徳宏 先生

論文名

RECK Is Up-Regulated and Involved in Chondrocyte Cloning in Human Osteoarthritic Cartilage

雑誌名

Nature Communications

​巻号ページ

2:Article No.251,March 2011

第18回

津嶋 秀俊 先生

論文名

CCAAT/enhancer binding protein β regulates expression of matrix metalloproteinase-3 in arthritis

小澤 英史 先生

論文名

Osteoarthritic Change Is Delayed in a Ctsk-Knockout Mouse Model of Osteoarthritis

大久保 匡 先生

論文名

Semaphorin 3A Is Expressed in Human Osteoarthritic Cartilage and Antagonizes Vascular Endothelial Growth Factor 165-Promoted Chondrocyte Migration ; An Implication for Chondrocyte Cloning

石川 正洋 先生

論文名

Lectin-like Oxidized Low-Density Lipoprotein Receptor 1 Signal Is a Potent Biomarker and Therapeutic Target for Human Rheumatoid Arthritis

雑誌名

Annals of the Rheumatic Diseases

​巻号ページ

Vol.71, 2012, pp99-107

雑誌名

ARTHRITIS & RHEUMATISM

​巻号ページ

Vol.64, No.2,  Feb.2012, pp454-64

雑誌名

ARTHRITIS & RHEUMATISM

​巻号ページ

Vol.63, No.10,  Oct.2011, pp3000-9

雑誌名

ARTHRITIS & RHEUMATISM

​巻号ページ

Vol.64, No.4,  Apr. 2012, pp1024-34

佐々木 宏 先生

論文名

Autophagy Modulates Osteoarthritis-Related Gene Expression in Human Chondrocytes

雑誌名

ARTHRITIS & RHEUMATISM

​巻号ページ

Vol.64, No.6,  Jun. 2012, pp1920-28

第19回

吉岡 裕 先生

論文名

Suppression of hyaluronan synthesis alleviates inflammatory responses in murine arthritis and in human rheumatoid synovial fibroblasts.

矢野 文子 先生

論文名

A novel disease-modifying osteoarthritis drug candidate targeting Runx1.

保坂 陽子 先生

論文名

Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development.

清藤 直樹 先生

論文名

Interruption of glycosphingolipid synthesis enhances osteoarthritis development in mice.

 瓜田 淳 先生

論文名

Alterations of high-mannose type N-glycosylation in human and mouse osteoarthritis cartilage.

雑誌名

Arthritis Rheum.

​巻号ページ

65(5):1160-70

雑誌名

Ann Rheum Dis.

​巻号ページ

72(5):748-53

雑誌名

Proc Natl Acad Sci U S A.

​巻号ページ

110(5):1875-80

雑誌名

​巻号ページ

64(8):2579-88

Arthritis Rheum.

雑誌名

​巻号ページ

63(11):3428-38

Arthritis Rheum.

第20回

橋本 功 先生

論文名

Regulated Transcription of Human Matrix Metalloproteinase13(MMP13)and Interleukin-1β(IL1B)Genes in Chondrocytes Depends on Methylation of Specific Proximal Promoter CpG Sites

村田 浩一 先生

論文名

Inhibition of miR-92a Enhances Fracture Healing via Promoting Angiogenesis in a Model of Stabilized Fracture in Young Mice

大関 信武 先生

論文名

Transplantation of Achilles Tendon Treated With Bone Morphogenetic Protein 7 Promotes Meniscus Regeneration in a Rat Model of Massive Meniscal Defect

波多 賢二 先生

論文名

Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes 

雑誌名

THE JOURNAL OF BIOLOGICAL CHEMISTRY

​巻号ページ

288(14):10061-10072

雑誌名

Journal of  Bone and Mineral Research

​巻号ページ

29(2):316-326

雑誌名

ARTHRITIS&RHEUMATISM

​巻号ページ

65(11):2876-2886

雑誌名

NATURE COMMUNICATIONS

​巻号ページ

4,Article number:2850(2013)

Annals of the Rheumatic Diseases

雑誌名

​巻号ページ

73(7):1397-1404

松崎 時夫 先生

論文名

Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice